LIAC | SIT Sordina logo

PRESENTATION

LIAC is a lightweight intraoperative linear accelerator designed to be integrated into any operating room without structural modifications, facilitating the application of intraoperative radiotherapy (IOeRT) in oncological surgeries. Its ergonomic and compact design allows easy maneuvering and mobility on different types of floors, as well as being transportable in conventional stretcher lifts.

Radixact 2

GENERAL INFORMATION

Self-shielded and mobile linear accelerator for intraoperative radiotherapy LIAC with electrons.

  • It is the first compact, mobile and self-shielded linear accelerator that quickly and safely delivers IOERT to cancer patients during the surgical procedure of tumor removal. Intraoperative electron radiation therapy (IOERT) delivered with LIAC means new hope for cancer patients, allowing surgeons and radiotherapists to irradiate the tumor at the same time as surgery.
  • IOERT is the direct application of radiation with electrons to residual tumors or the tumor bed during surgery for cancer resection. Electron beams are useful for the administration of intraoperative radiotherapy since, depending on the energy of the electrons, the dose drops rapidly when hitting the target, with less damage to surrounding healthy tissues.

    IOERT is also called “precision radiotherapy” since the doctor can see the tumor, normal tissues can be excluded from the field and critical structures can be protected.

    It has the particularity of being administered during surgery, when residual tumor cells, often microscopic, are more vulnerable and can be destroyed more easily. It can also be combined with external radiotherapy, resulting in shorter treatments and a lower total dose.
  • ✅ Immediate results: 2 minutes of treatment with LIAC, in the operating room, are enough to destroy the residual cancer cells in the tumor bed.

    ✅ Shorter treatment time: LIAC not only reduces surgery time and infection risks, but also shortens pre- and postoperative radiotherapy treatment.

    ✅ Reduces or eliminates patient stress: they do not have to be transported to or from the external radiotherapy treatment center because they can now be treated only once, during surgery, making treatment more tolerable for the patient.

    ✅ Directly irradiates residual cancer cells.

    ✅ Eliminates damage to healthy tissue surrounding the cancer.

    ✅ Reduces local recurrence rate: prevents the spread of cancer cells after surgery.

    ✅ Fewer side effects: LIAC directly irradiates the affected tissue allowing the surgeon to protect healthy organs and tissues, achieving better local control of the tumor.
  • Intraoperative electron radiation therapy (IOERT) has great potential in the treatment of cancer. Before LIAC, most IOERT patients were transferred from the operating room to the radiation suite to receive their IOERT treatment, under anesthesia and with an open wound, with all the complications that this entailed.

    After treatment, they were transferred back to the operating room to complete the surgery.

    This was inefficient for both the surgical and radiotherapy departments, and also put the patient's safety at risk by subjecting them to a longer surgical intervention, with a longer time under anesthesia and risks of infection when being transferred outside the sterile environment.

    LIAC has changed the way cancer patients are treated around the world.

INSTALLATION AND START

+Media
+Application areas
+Brochures
+Papers
Pictures
Videos

Application areas

The clinical applications of intraoperative electron radiotherapy with the Liac system are diverse and are mainly used in the treatment of certain types of cancer.

✅ Breast cancer:

• IOERT is mainly used in the treatment of breast cancer, especially in patients with localized tumors or in those who have undergone breast-conserving surgery (such as a lumpectomy). A dose of radiotherapy is administered to the tumor bed immediately after the tumor is removed, which helps to eliminate possible residual cancer cells in the affected area and reduces the risk of local recurrence.
• This technique is useful both in cases of early breast cancer and in those in which affected lymph nodes have been removed.

✅ Rectal and colon cancer:

• In rectal or colon cancers, IOERT is used in combination with surgery to remove the tumor and deliver radiotherapy to the resection margins, which helps to reduce the risk of local recurrence. This is especially useful in cases where the tumor is close to critical structures and radiation therapy to healthy tissue is to be avoided.
• It is usually applied after surgical resection, to ensure that any residual cancer cells are treated with radiation therapy, minimizing the risk of local metastasis.

✅ Pancreatic cancer:

• In some cases of pancreatic cancer, IOERT is used after surgical resection of the tumor.

✅ Gynecological cancer:

• To treat cancer of the uterus, ovaries, or cervix, intraoperative electron radiation therapy may be applied after the tumor has been removed. This is used to treat hard-to-reach areas or to deliver an additional dose of radiation therapy to resection margins and areas at risk.

✅ Head and neck cancer:

• For tumors located in the head and neck, such as those in the oral cavity, pharynx, or larynx, intraoperative electron radiation therapy can be used to treat areas close to important structures, such as nerves and blood vessels.

✅ Melanoma:

• In the treatment of melanoma (especially in areas where the tumor is close to vital or difficult-to-treat structures), IOERT can be useful to deliver precisely localized radiation therapy after the tumor is excised. This helps eliminate remaining malignant cells that may have been left at the edges of surgery.

✅ Esophageal cancer:

• For patients with esophageal cancer, IOERT is used as part of a multimodal treatment that includes surgery and radiation therapy. Intraoperative radiation therapy can treat areas that are difficult to access or where external radiation therapy cannot reach without damaging other critical organs.

✅ Sarcomatous tumors:

• In sarcomas (soft tissue tumors), intraoperative radiotherapy can be applied during surgical resection to ensure that the areas surrounding the tumor are adequately treated. This is crucial for tumors that are located in difficult locations or when surgery cannot be completely radical due to the location of the tumor.

Brochures

Liac Overview - Folleto de DeLeC Científica

Papers


El uso de radioterapia intraoperatoria (RIO)

Revisión sistemática de la H&N intraoperatoria

IORT: una experiencia multicéntrica italiana

Actualización de 2016 Directrices ASTRO APBI

Desafíos y oportunidades de la radiación FLASH

¿POR QUÉ NOSOTROS?

We are the best partner in tech

for the comprehensive development of medical programs
Contact us